Scientist, In Vitro

Recursion is the clinical-stage biotechnology company industrializing drug discovery by decoding biology. Recursion leverages sophisticated machine-learning algorithms to infer biological relationships. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.

While we offer cutting-edge tools and an amazing lab, the secret sauce is our people. Our organization structure and culture isn't driven by politics or ego, it is designed first and foremost to help you do your best work. We live and work by values that we see as the strategic differentiators that give us a competitive advantage, supporting better and faster work without burnout and encouraging us to make leaps where others take steps. This is a place where people in every role and every level make the bold bets that create large leaps forward on a regular basis.

The Impact You’ll Make

Recursion Pharmaceuticals is at the forefront of re-imagining drug discovery through the integration of automated cell biology, generation of high-dimensional and diverse data sets, and sophisticated analytics. We are seeking a Scientist to design and execute multi-omics experiments in the areas of high-throughput as well as single-cell transcriptomics methods. This scientist will be a crucial part of our multi-year long Neuroscience program and will be part of our large cross-functional team working with  human iPSC derived neural cell types and relevant disease models. As a scientist and team member in the Neuroscience group you will focus on the differentiation and characterization of hPSC models involving various cell types such as neuronal subtypes and glial cells such as astrocytes and microglia. You will enable our HTS team to expedite screening at industry-leading scale to generate petabytes of high-dimensional data from human cells. You will work cross-functionally to develop robust, scalable systems and grow our Map of Biology. In this role, you will:

• Enable Recursion to build Maps of Biology through the molecular characterization of hiPSC derived neural cell types and human disease models
• Design in vitro cell transcriptomics screening tools that allow us to understand genetic and pharmacological perturbations in relevant neuronal disease models. 
• Achieve work with internal and external partners to rapidly deliver high-quality in vitro data to enable decision making on a rapidly growing portfolio of pre-clinical programs in oncology and neuroscience
• Deliver by performing in vitro biology assays that generate the data that helps us understand and optimize our programs and molecules
• Train team members to perform newly developed methods for scale to enable 100’s to 1000’s of 1536 well microplates screened per week
• Collaborate with data scientists, computational biologists, chemists, and clinical strategists across the organization to develop Recursion's data-to-therapeutic pipeline to discover new impactful medicines and ultimately serve patients

The Team You’ll Join 

Reporting to the VP, Advanced Translational Modeling, you'll join our newly formed team focused on the utilization of human pluripotent stem cells (hPSCs) to model neurodegenerative diseases. You will be joining a fast-paced team of multi-disciplinary scientists who are focused on bringing new therapeutics to patients at an accelerated pace. This team helps Recursion develop, refine, and characterize state-of-the-art differentiation technology and advanced disease models at a large scale for one of the world’s leading companies in AI-guided drug discovery. This high performing team is bold, creative, and has a team-first mindset alongside a deep passion for exploring the unknowns of neuroscience.

The Experience You’ll Need

• PhD in Neuroscience, Biotechnology or related field, or MS with 3+ years of relevant pharma or biotech industry experience
• Demonstrated ability to understand, communicate, and work collaboratively to deliver on cross-functional objectives
• Subject matter expertise and hands-on laboratory experience designing, troubleshooting, and executing bulk and/or single cell high throughput sequencing experiments.
• Experience with design, execution, and analysis of diverse in vitro neuroscience methods (high-content imaging, electrophysiology, molecular biology)
• A passion for working in a fast-paced environment where you’ll leverage creativity and independent thinking when deriving, expanding, banking and genetically perturbing challenging human cell types
• Demonstrated capacity to independently manage and coordinate scientific projects with an owner’s mindset. Ability to lead projects, mentor, and train others
• Efficient and effective communication of research findings and interpretation in written and verbal form
• Strong interpersonal skills, desire to work in a team that trusts and supports each other

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