Scientist, Reverse Translation

At Genmab, we're committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

The Role

Genmab is seeking a highly motivated scientist to join our Reverse Translation team, which is part of the ground-breaking Precision Medicine and Translational Medicine Research teams. These teams generate and interpret high throughput omic data to uncover and validate the mechanism of action and pharmacodynamic and drug sensitivity biomarkers for our Genmab products, and of commercial and preclinical samples. The Reverse Translational Disease Biology research group is dedicated to discover and formulate testable hypotheses regarding resistance mechanisms and pathways to standard of care regimens and Genmab therapeutic antibodies.

Responsibilities

• Research:
  • Be motivated to identify features of tumor and/or microenvironment that in resistant patients hinder the immune response to the treatment applied, and that can make the tumor vulnerable to alternative treatment approaches.
  • Be driven to understand cells, their internal circuits, and their interactions in health and disease, to discover and deliver new targets and treatment approaches.
  • Translate findings into testable hypotheses regarding rational therapy combinations or drug sequencing, design and oversee laboratory experiments, utilizing techniques such as molecular biology, cell culture, and animal models to explore disease mechanisms and potential treatments.

• Data Analysis: Learn to utilize the vast array of internal and external data from clinical trials, research collaborations, EMRs, RWE, and commercially purchased data sets, to drive deep disease biology knowledge, to help refine preclinical and early development approaches for our Genmab portfolio, and to help validate targets and pathways of interest.

• Collaboration: Work closely with interdisciplinary teams, including computational biologists and oncology/immunology biologists, clinicians, and statisticians, to ensure integrated and effective research approaches.

• Communication: Contribute to the presentation of your findings at various internal forums and meetings, scientific conferences and publish results in peer-reviewed journals.

• Innovation: Stay abreast of the latest scientific advancements and technologies in the field and incorporate innovative approaches into research strategies.

• Regulatory Compliance: Learn about and to apply regulatory compliance and ethical standards of your research activities.

Requirements

• You have an immune-oncology/oncology/immunology background and hold a PhD degree in the field of molecular biology, biomedical sciences, immunology, biotechnology or bioinformatics, or a relevant other topic.
• 2+ years of post-doctoral experience in relevant technical field (industry or academia)
• You are driven to provide biological interpretations of your results to teams with diverse scientific backgrounds.
• During your PhD, you have designed, planned, executed, and analyzed experimental studies using molecular and cell biology techniques
• You have an interest in omic data processing, data analysis and applied statistics. Experience with Python or R is a plus.
• You are enthusiastic, creative, goal orientated, pro-active and out-of-the-box thinking with a strong ability to work independently.
• Publication record demonstrating relevant experience.

Level will be commensurate with candidate's experience. This position can be based in Princeton, NJ or Utrecht, NL.

For US based candidates, the proposed salary band for this position is as follows:

$75,000.00---$125,000.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as bonuses.

About You

• You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
• You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with diverse backgrounds
• You are determined to do and be your best and take pride in enabling the best work of others on the team
• You are not afraid to grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you're in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Founded in 1999 in Copenhagen, Denmark, Genmab is an innovative biotech company that has become a leader in antibody biology and innovation. Our product pipeline and next-generation antibody technologies are the result of our strong company culture, a deep passion for innovation, and desire to transform cancer treatment and serious diseases.

When you work with us, you'll be part of a warm, fun, dynamic community, and team up with some of the best, most authentic individuals in locations around the world, who care deeply and share in a relentless drive to innovate and create transformational medicines. People who are candid, impact-driven, and a little unconventional; who seek out and embrace the opportunity to build new and bold futures within a rapidly growing and innovative biotech company; who bring their full selves to work and show up for each other - rolling up their sleeves to get the job done. This translates into a place where you can be authentically you; are empowered to innovate, build solutions, and execute; feel cared for and supported in growth; and are a critical part of changing the lives of patients around the world through transformative cancer treatment.

Our commitment to diversity, equity, and inclusion

We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website.

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website https://www.genmab.com/privacy.

Please note that if you are applying for a position in the Netherlands, Genmab's policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.