Senior Associate Scientist, Lead Development (Contract)

The Role:

The Lead Development group at Life Edit discovers new genome editing systems and establishes new editing capabilities and optimizes them to support efforts developing curative gene editing therapies and gene edited cell therapies. We are looking for an enthusiastic, competent, and self-motivated Senior Associate Scientist with a strong background in mammalian cell culture and genome editing to help expand our mammalian cell screening efforts.

Here’s What You’ll Do:

• Evaluate Life Edit gene editing systems in mammalian cells to identify optimal engineered systems for further therapeutic discovery and development
• Evaluate and troubleshoot protocols for the delivery of Life Edit gene editing systems to different primary cells and cell lines
• Follow current SOPs with an eye towards future improvements
• Support common workflows with the team to maximize efficiencies and progress
• Flexibly communicate and plan support work to enable rapid experimentation
• Analyze experimental data and present scientific results at team research meetings

Requirements:

• Senior Associate Scientist: Bachelor’s degree in Cell Biology, Biology, Molecular Biology, or a related field with 2+ years of experience or master’s degree (0 years experience) in academic or biopharmaceutical organization
• Expertise culturing, transfecting, and analyzing cell lines and primary cells
• Experience delivering nucleic acids or RNA into mammalian cells using multiple delivery methods including nucleofection, lipofection, and lipid nanoparticles
• Experience with modern molecular biology techniques including DNA/RNA extraction, PCR, qPCR, NGS, Flow cytometry and ELISAs
• Experience with molecular cloning techniques including bacterial transformation, nucleic acid purification, and Gibson assembly style cloning
• Comfortable with the execution of computational pipelines with appropriate training
• Experience with laboratory automation and liquid handlers is a plus
• Experience maintaining and organizing ELN documentation
• Demonstrated ability to work independently and collaborate in a team-oriented environment
• Outstanding written and verbal communication skills
• Industry experience strongly preferred